Alzheimer's Disease Research Center

Current Projects

Alzheimer’s Disease Research Center (2005-2010):

Project 1 Mapping substrate/y-secretase interactions
Rahpael Kopan, Ph.D. (Project Leader)

Project 3 PET Amyloid Imaging in the Elderly to Evaluate DAT Risk
Mark Mintun, MD

Healthy Aging & Senile Dementia Program Project (2004-2008):

Project 1 Dementia Assessment in the Community
John C. Morris, MD

Project 2 Novel Biomarkers to Predict Alzheimer's Disease
David Holtzman, MD

Project 3 Attention Profiles in Healthy Aging and Early State DAT
David Balota, Ph.D.

Project 4 Predicting Cognitive Decline in Nondemented Elder Subjects
John Csernansky, MD

Current & Recent Pilots

5/07 – 4/08

PET Agent for Imaging of P-glycoprotein (Pgp) mediated transport activity in Alzheimer’s disease.
Sharma, Vijay, Radiology

Neurology and Radiology, se of 11C-PIB to determine risk of recurrence of lobar intracerebral hemorrhage: A pilot study.
Zazulia, Allyson

Roles of Aβtype lamins on telomere metabolism and premature aging.
Gonzalo, Susana

5/06 – 4/07:

Eye movements during visual search in healthy aging and very mild DAT
Richard A. Abrams, PhD

Emotional Aging: Preservation of Function in the Elderly and Alzheimer's Patients
Randy J. Larsen, PhD

Selective synapse loss and β-amyloid deposition in the Tg2576 mouse
Hongxin Dong , MD PhD

5/05 – 4/06:

Genetic Factors Modulating Quantitative Traits in LOAD
Anthony Hinrichs, Psychiatry

Metabolic Consequences of PINK 1 Mutations
Paul Kotzbauer, Neurology

Prospective Memory in DAT and APOE Genotype
Mark McDaniel, Psychology