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John C.
Morris, MD, is the Principal Investigator and Director for the following grants
from the National Institute on Aging (NIA):
Alzheimer’s
Disease Research Center
(ADRC;
P50-AG05681; 1985 - present)
Healthy Aging
& Senile Dementia
Program
Project (HASD; P01-AG03991; 1984 – present)
Antecedent
Biomarkers for AD: The Adult Children Study
(ACS; P01-AG26276; 2005 – present)
The ADRC, HASD and ACS
engage faculty and staff from the Department of Neurology and other
Departments at Washington University in the study of cognitive aging
and dementia. Alzheimer's disease (AD) is a central focus both
research and education. These primary grants provide the core data
acquisition and management structures for numerous other
grant-funded and pilot research efforts by investigators at
Washington University.
Research efforts through the ADRC and HASD
focus on identifying causal and risk factor mechanisms in the
development of AD and other dementias, biochemical and
clinical-behavioral indicators of disease onset and progression, and
potential therapeutic and preventative agents. Research participants
and family members take part in annual, longitudinal assessments
through the ADRC's clinical office, the Memory and Aging Project (MAP).
MAP participants are also invited to take part in various ancillary
studies supported by the ADRC, such as clinical drug trials, and
provide biological and imaging specimens for basic research projects
in affiliated labs across the University.
The ACS builds
on and focuses work conducted through the ADRC and HASD over the
past two decades, with a goal of identifying antecedent biomarkers
for the early and preclinical detection of AD. |
